AutoOligo Process 8000 Nucleic Acid Synthesizer 400 mmol (CAT#: STEM-BC-0399-ZJF)

Highlights

Large-scale 60-400 mmol synthesis
Commercial production suitability
High automation level

Cat Number: STEM-BC-0399-ZJF

Application: for commercial oligonucleotide production

Model: AutoOligo Process 8000




Description

The AutoOligo Process 8000 is a large-scale nucleic acid synthesizer for commercial solid-phase oligonucleotide production. It supports 60-400 mmol synthesis scale and is intended for large-batch manufacturing. The system can support kilogram-level product harvest per synthesis batch under appropriate process conditions. Sanitary metering diaphragm pumps and multiple detectors provide controlled fluid delivery and process monitoring. UV, conductivity, pressure, and temperature detection are integrated before and after the column. The system is suitable for post-launch production of small nucleic acid products and large-scale API preparation. It supports quality manufacturing standard-related quality documentation and validation workflows. Explosion-proof certification supports use in solvent-intensive synthesis environments.

Specification

Synthesis Scale: 60-400 mmol
Pump Type: 3 sanitary metering diaphragm pumps
Mass Flow Meters: 3
UV Detectors: 2 pre-column and post-column
Conductivity Detectors: 2 pre-column and post-column
Pressure Detectors: 8
Temperature Detectors: 2 pre-column and post-column
Monomer Inlets: 17
Reagent Inlets: 8 reagents plus 4 solvents
Waste Outlets: 4
Explosion-Proof Rating: EX pzc IIB T4

Features

Large-scale 60-400 mmol synthesis
Commercial production suitability
High automation level
Real-time full-process monitoring
quality manufacturing standard documentation support
Validation service support
regulatory compliance 21 CFR Part 11 software support
Explosion-proof certified system

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