Analysis of GNAI3 Gene (Mutation) by RT-qPCR (CAT#: STEM-MT-1200-LGZ)

Introduction

Official Full Name: G protein subunit alpha i3
Also known as: 87U6; HG1A; ARCND1; ARCODS
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway.