Alkaline Lysis (pDNA Extraction) System (CAT#: STEM-BC-0249-ZJF)

Highlights

Precise quantitative control of alkaline lysis process parameters

Multi-scale capability - single system handles both pilot and production volumes

One-button CIP

Cat Number: STEM-BC-0249-ZJF

Application: Commercial-scale plasmid DNA (pDNA) extraction and purification from E. coli fermentation broth; quality manufacturing standard plasmid manufacturing for vaccines and gene therapy

Model: ACL System (Alkaline Cell Lysis System)




Description

China's first in-line alkaline lysis system for large-scale, sanitary-grade pDNA preparation from E. coli. Addresses the industry-wide challenges of scale-up, inter-batch supercoiling ratio variability, and low extraction yield. Available in stainless steel and single-use (SU) configurations.

Specification

Scalable to multiple fermentation volumes
single-unit multi-scale operation
Single-use (SU) version: replaceable tubing and accessories available
CIP: one-button automated CIP function

Features

Precise quantitative control of alkaline lysis process parameters
Multi-scale capability - single system handles both pilot and production volumes
One-button CIP
SU version with replaceable tubing eliminates cleaning validation
Robust construction for continuous high-density long-term production
Simple operation and low maintenance cost
Solves scale-up, batch-to-batch supercoiling variability, and yield challenges in pDNA production

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High-quality products

High-quality products

Reliable performance

Wide range of applications

Wide range of applications

For various laboratory needs

Expert support

Expert support

Professional service team

Fast delivery

Fast delivery

Global shipping