5 Input Chip, 3D, 150 µm, dolomite (CAT#: STEM-ME-0369-WXH)

The 5 Input Chip 3D 150 µm is a glass microfluidic device designed on the layout described in papers by Jahn (2007) Microfluidic Directed Formation of Liposomes of Controlled Size (DOI: 10.1021/la070051a). The new 3D pore structure enables particle precipitation to occur in the bulk of the fluid avoiding particle-channel wall interaction. The chip is particularly suitable for the controllable formation of a central laminar focused stream sheathed between two or four lateral antisolvent streams. The design allows reproducible diffusive mixing at the two liquid interfaces for polymer particle nanoprecipitation and nanoliposome self-assembly.

Channels cross-section (depth x width): 150 μm x 160 μm
3D pore cross-section (depth x width): 70 μm x 100 μm
Side channels: Fully combined prior to junction
Angle at the junction point: 72°
Surface coating: Hydrophilic
Focused stream thickness: 10 – 150 μm
Chip size (length x width x thickness): 22.5 mm x 15 mm x 4 mm
Number of inputs: 5 (edge)
Number of outputs: 1 (edge)
Channel length after junction: 16 mm
Surface roughness of channels (Ra): 5 nm
Max. operating pressure: Up to 30 bar
Material: Glass
Fabrication: HF etching and thermal bonding

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