15Q-HNmicro / 30Q-HNmicro Anion Exchange Chromatography Medium 30 mg/mL (CAT#: STEM-BC-0413-ZJF)

15Q-HNmicro and 30Q-HNmicro are anion exchange chromatography media for oligonucleotide separation by charge difference. They are designed to separate oligonucleotides from failed sequences within the 5-50 base range. The media support separation of N-1 and N+1 impurities. Both formats use PS-DVB matrix particles with different particle sizes. Defined ion exchange capacity and dynamic loading support process selection. The media tolerate a wide pH range and are stored in ethanol solution. Low backpressure supports practical column operation. They are suitable for high-resolution oligonucleotide purification workflows.

15Q-HNmicro Matrix: PS-DVB
15Q Particle Size: 15 μm
15Q Ion Exchange Capacity: 0.2-0.25 meq/mL
15Q Dynamic Loading: 30 mg/mL nucleotide
30Q Matrix: PS-DVB
30Q Particle Size: 30 μm
30Q Ion Exchange Capacity: 0.18-0.22 meq/mL
30Q Dynamic Loading: 25 mg/mL nucleotide
pH Stability: 2-13
Storage: 20% ethanol at 2-8°C

High resolution
High loading capacity
Acid tolerance
Alkali tolerance
Salt tolerance
Low column backpressure
High column efficiency
Low nonspecific interaction

STEM-BC-0225-ZJF
STEM-BC-0226-ZJF
STEM-BC-0227-ZJF
STEM-BC-0228-ZJF
STEM-BC-0229-ZJF