Direct determination of heavy elements in biological media by spark source mass spectrometry (CAT#: STEM-ST-0274-LJX)

Introduction

The determination of trace heavy elements in biological media by spark source mass spectrometry is studied. Direct analysis of serum, homogeneous liver and urine without prior ashing. Through reasonable control of spark parameters, the spark performance can be effectively improved. Organic interference can be kept in the lower mass range, thus leaving the higher range unaffected by such interfering ions. The elements studied are Pt, Au, Hg, Ti, Pb and Bi. Calibrate curves by using an internal image developer and elements. Concentrations below 1ppm have been measured from a single exposure. The unique sampling procedure and its feasibility as a routine pathological tool are discussed.

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Principle Applications Procedure Materials Notes Related Products

Principle

By using vacuum spark discharge, the energy accumulated in a small volume can make the material in the volume suddenly evaporate and ionize, so as to obtain the characteristic ion current information.

Applications

(1) Solid spark source mass spectrometry: impurity analysis of high-purity materials, which can be applied to semiconductor materials, non-ferrous metals, and building materials industries;
(2) Gas isotope mass spectrometry: determination of stable isotopes C, H, N, O, S and radioactive isotopes Rb, Sr, U, Pb, K, Ar, which can be applied to geology, petroleum, medicine, environmental protection and agriculture.

Procedure

(1) An electric field is applied between the electrodes to ionize part of the carrier gas (such as argon) in the electric field;
(2) The "cathode ray" or "anode ray" generated by ionization accelerates in the direction of the opposite polarity in the residual gas, bombards the anode or cathode, and vaporizes a part of the substance to be measured on the plate;
(3) Part of the atoms of the vaporized substance are ionized in the subsequent discharge process.

Materials

• Sample Type:
Biological media

Notes

Before starting the machine, check whether the water (water cooler), electricity, gas (argon/nitrogen), temperature, humidity, and exhaust air of the instrument are normal.

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