WeSPR One Biomolecular Interaction Analyzer

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WeSPR One

Precision Interaction Analysis

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WeSPR One Biomolecular Interaction Analyzer (STEMart Original)

The WeSPR One Biomolecular Interaction Analyzer is a compact, easy-to-use system designed to deliver affinity, kinetic, and active concentration data with high precision. Powered by innovative MetaSPR (Metasurface Plasmon Resonance) technology, WeSPR One enables label-free, real-time analysis of biomolecular interactions across a broad range of applications.

From protein interaction studies to biomolecular mechanism analysis, WeSPR One accelerates discovery by providing high-quality data with minimal sample requirements. Its intuitive, guided software interface eliminates steep learning curves, making it an accessible yet powerful solution for research in both academic and industrial laboratories.

Applications

WeSPR One supports a wide range of applications, including antibody development, drug discovery, cell therapy, gene therapy, vaccine development, bioproduct synthesis, and in vitro diagnostics.

SPR Workflows For Small Molecule Affinity Screening And Antibody Screening With Sensorgram Results (STEMart Original)

Features

Desktop-Scale Flexibility: Compact and personal instrument with a high-precision fluidic system, minimizing buffer/sample mixing and enabling dual-buffer online switching.

Intuitive Operation: Guided software interface for easy adoption; zero maintenance and near-zero training requirements.

Reliable Performance: Built-in real-time degassing reduces bubble interference, ensuring stable and accurate results.

High Compatibility: Low bulk effects with broad biomolecule compatibility – supports antigens/antibodies, proteins/peptides, nucleic acids, viral particles, liposomes, exosomes, cells, supernatants, serum, and plasma.

Extended Throughput: Automated sample injection with long-duration unattended operation (up to 48h).

WeSPR One System Features (STEMart Original)

Specifications

Parameter	Specification
Automation Level	Semi-automated
Channels	2 (1 detection, 1 reference)
Injection Volume	10–500 μL
Flow Rate	5–200 μL/min
Temperature Range	4–40 °C
Sample Throughput	Dual 96-well plates
Sample Types	Compatible with diverse biological samples, including buffers with DMSO, plasma, serum, small molecules, proteins, nucleic acids, polysaccharides, lipids, viruses, and more
Buffer Selection	Two buffer solutions with automated switching
Concentration Range	≥1 pM
Association Rate Constant (ka)	Proteins: 10¹–10⁹ M⁻¹s⁻¹; Small molecules: 10³–5×10⁷ M⁻¹s⁻¹
Dissociation Rate Constant (kd)	10⁻⁶–10⁻¹ s⁻¹
Affinity Range (KD)	pM–mM
Minimum Detectable Mass	150 Da
Short-Term Baseline Noise	<1.2 RU/min
Long-Term Baseline Noise	<3 RU/min
Cycle Time per Analysis	5–15 min
Data Display	Real-time sensorgrams, curve fitting, calibration curves, concentration tables, kinetic data tables, epitope analysis plots, and bar charts
Data Export Formats	Excel, TXT
Unattended Operation	Automated injection system supporting up to 48 hours continuous analysis
Dimensions	400 × 360 × 480 mm
Weight	30 kg
Computer Interface	USB

The WeSPR One Analyzer offers precision, simplicity, and versatility for real-time, label-free biomolecular interaction studies. With its desktop footprint, guided workflow software, and compatibility with a wide range of biomolecules, it is an ideal solution for researchers seeking to accelerate discovery in antibody development, drug discovery, vaccine research, and beyond.

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