WeSPR HT8 Fully Automated Multifunctional Molecular Detection System

WeSPR HT8

Automation Driving Discovery

Features

Fully Automated: Complete end-to-end automation, freeing researchers from manual intervention.

Extended Unattended Operation: Up to 72 hours continuous analysis with seamless sample handling.

Zonal Temperature Control: Independent temperature regulation for detection, sample, and reaction zones enhances experimental precision.

Parallel Throughput: Supports 8 optical channels with up to 4 × 96-well plates, enabling large-scale kinetic or quantitative studies.

Multifunctional Applications: Kinetic/affinity profiling, fragment and small-molecule screening, epitope mapping, immunogenicity, thermodynamics, quantitative assays, ELISA-equivalent functions.

Broad Sample Compatibility: Capable of analyzing purified biomolecules and complex samples (buffers with DMSO, serum, plasma, supernatants, lysates, crude extracts).

Flow-Free Design: No tubing, minimal maintenance, consistent data quality.

Ultra-Fast Quantification: IgG quantitation of 96 samples completed in as little as 5 minutes.

Specifications

Parameter	Specification
Automation Level	Fully automated
Sample Capacity	Up to 4 × 96-well plates
Optical Channels	8 fiber-optic detection channels
Applications	Kinetics & affinity characterization, screening, single-cycle kinetics, small molecule interaction analysis, fragment-based screening, epitope mapping & pairing, immunogenicity, quantitative analysis, thermodynamics, ELISA & microplate reader functionality
Refractive Index Range	1.33–1.43
Sample Volume	2–200 μL, non-destructive
Temperature Range	4–70 °C
Shaking Speed	200–1200 rpm
Sample Platform Speed	2 m/s
Data Display	Real-time sensorgrams, curve fitting, calibration curves, concentration tables, kinetic data tables, epitope mapping plots, bar charts
Data Export Formats	Excel, TXT
Sample Types	Small molecules, peptides, proteins, antibodies, nucleic acids, polysaccharides, lipids, viruses, cells, and complex biological samples (serum, plasma, supernatants, lysates, buffers with DMSO)
Throughput	Up to 8 samples in parallel; maximum 96 samples per run; supports continuous analysis of 4 × 96 plates
Association Rate Constant (ka)	Proteins: 10¹–10⁷ M⁻¹s⁻¹; Small molecules: 10³–5×10⁷ M⁻¹s⁻¹
Dissociation Rate Constant (kd)	10⁻⁶–10⁻¹ s⁻¹
Affinity Range (KD)	pM–mM
Minimum Detectable Mass	150 Da
Analysis Time	<10 min for 8-sample affinity assays; up to 12h real-time kinetics; minimum 5 min for 96-sample screening
Baseline Noise (RMS)	<0.01 RU
Baseline Drift	<0.005 RU/min
Quantitative Throughput	Up to 96 samples simultaneously
Protein Concentration Range	0.05–1000 μg/mL
Quantitation Speed	96 IgG samples in 5 minutes
Unattended Operation	Up to 72h automated runs

WeSPR HT8 In A Laboratory (STEMart Original)

The WeSPR HT8 sets a new standard for high-throughput automated biomolecular interaction analysis. With 72-hour unattended operation, zonal temperature control, and large-scale sample handling, it empowers laboratories to accelerate discovery and development while ensuring reliable, high-quality data. Its combination of throughput, automation, and versatility makes it a leading solution for advanced biopharmaceutical and life science research.

Online Inquiry

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