WeSPR 200 Multifunctional Molecular Detection System

WeSPR 200

Precision Enhanced by Temperature

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WeSPR 200 Multifunctional Molecular Detection System (STEMart Original)

The WeSPR 200 is an advanced, high-throughput, flow-free molecular interaction analyzer equipped with an integrated temperature control module. Built on MetaSPR (Metasurface Plasmon Resonance) technology, it provides label-free, real-time biomolecular interaction analysis with improved sensitivity and reproducibility.

Designed to handle both purified and complex biological samples, the WeSPR 200 delivers reliable kinetic, affinity, epitope, and quantitative analysis while minimizing preprocessing. With its compact footprint, parallel channel capacity, and precise thermal regulation, the system enhances assay consistency and supports a broad spectrum of research applications.

Features

Temperature Control Module: Enables precise incubation and analysis across a wide range of experimental conditions.

Parallel Analysis: Supports up to 8 optical channels and dual 96-well plates for high-throughput workflows.

Versatile Applications: Provides kinetic/affinity profiling, fragment screening, epitope mapping, immunogenicity testing, thermodynamic analysis, quantitative assays, and ELISA-equivalent functions.

Broad Sample Compatibility: Compatible with complex matrices as well as purified biomolecules, reducing preparation time.

Flow-Free Design: Eliminates fluidic maintenance, ensuring straightforward and reliable operation.

Enhanced Sensitivity: Low baseline noise and drift deliver higher data quality for challenging samples.

WeSPR 200 Features (STEMart Original)

Specifications

Scientist Operating WeSPR 200 (STEMart Original)

Parameter Specification
Automation Level Semi-automated
Optical Channels 8 independent fiber-optic detection channels
Applications Kinetics & affinity characterization, screening, single-cycle kinetics, small molecule interaction analysis, fragment-based screening, epitope mapping & pairing, immunogenicity, quantitative analysis, thermodynamics, ELISA and microplate reader functions
Refractive Index Range 1.33–1.43
Sample Volume 2–200 μL, non-destructive
Incubation Function Supported
Temperature Range RT+4 to 50 °C
Shaking Speed 200–1200 rpm
Data Display Real-time binding curves, curve fitting, calibration curves, concentration tables, kinetic data tables, epitope mapping plots, bar charts
Data Export Formats Excel, TXT
Sample Types Small molecules, peptides, proteins, antibodies, nucleic acids, polysaccharides, lipids, cells, viruses, and complex matrices (DMSO buffers, serum, plasma, supernatants, lysates)
Throughput Up to 8 parallel analyses; maximum 96 samples per run
Buffer Selection Dual buffer switching
Association Rate Constant (ka) Proteins: 10¹–10⁷ M⁻¹s⁻¹; Small molecules: 10³–5×10⁷ M⁻¹s⁻¹
Dissociation Rate Constant (kd) 10⁻⁶–10⁻¹ s⁻¹
Affinity Range (KD) pM–mM
Minimum Detectable Mass 200 Da
Analysis Time <10 min for 8-sample affinity tests; up to 12h for real-time kinetic assays; maximum 96-sample screening with minimum 5 min run time, data sorted by binding signal
Baseline Noise (RMS) <0.005 RU
Baseline Drift <0.001 RU/hour
Quantitative Throughput Up to 96 samples simultaneously
Concentration Range 0.005–1000 μg/mL

The WeSPR 200 extends the performance of the WeSPR platform by combining high-throughput capability with precision temperature control, ensuring consistent and sensitive biomolecular interaction data. Its flow-free design, compatibility with complex samples, and broad application coverage make it an ideal choice for researchers working on drug discovery, antibody development, vaccine research, and molecular mechanism studies.

Contact us today to learn how WeSPR 200 can elevate your molecular interaction analysis with higher sensitivity and reproducibility.

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