WeSPR 100X Multifunctional Molecular Detection System

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WeSPR 100X

Compact Power, High Throughput

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WeSPR 100X Multifunctional Molecular Detection System (STEMart Original)

The WeSPR 100X is a compact, high-throughput, flow-free molecular interaction analyzer designed to deliver robust and versatile performance across diverse biomolecular research applications. By leveraging MetaSPR (Metasurface Plasmon Resonance) technology, the system enables label-free, real-time analysis of a wide range of biomolecular interactions, even with complex samples such as serum, plasma, cell culture supernatants, and lysates.

Supporting up to 96 samples in a single run with eight or more channels in parallel, the WeSPR 100X provides comprehensive kinetic, affinity, epitope, and quantitative analysis while minimizing sample volume and preprocessing steps. Its flow-free design eliminates routine fluidic maintenance, while the ability to recover samples makes it both cost-efficient and resource-friendly.

Application Case

The WeSPR 100X enables high-precision, label-free measurement of biomolecular interactions across a wide range of applications, including antibody screening, protein–ligand binding analysis, and kinetic or affinity characterization. Its high-throughput, flow-free design allows rapid and stable detection even with complex biological samples, offering reliable data for biopharmaceutical research and development.

WeSPR 100X Applications (STEMart Original)

The following example demonstrates the use of the WeSPR 100X in analyzing Protein A–IgG interactions, where multiple concentration gradients were measured in real time to generate high-quality kinetic and affinity curves, showcasing the system's accuracy and reproducibility.

Protein A–IgG Binding Kinetics Measured by WeSPR 100X (STEMart Original)

Features

Scientist Operating WeSPR 100X (STEMart Original)

High Throughput: Supports ≥8 channels in parallel with up to 96-sample capacity per run.

Multifunctional Detection: Delivers kinetic and affinity characterization, epitope mapping, quantification, fragment screening, thermodynamic studies, and ELISA-equivalent readouts.

Broad Sample Compatibility: Handles purified biomolecules as well as complex matrices (DMSO buffers, serum, plasma, cell supernatants, lysates), reducing sample preparation time.

Flow-Free Operation: Eliminates the need for fluidic tubing and maintenance, ensuring easy and reliable use.

Sample Recovery: Non-destructive testing allows sample reuse, reducing overall consumption.

Compact Design: Desktop-friendly instrument suitable for both academic and industrial laboratories.

Specifications

Parameter	Specification
Detection Principle	MetaSPR (Metasurface Plasmon Resonance)
Automation Level	Semi-automated
Channels / Throughput	≥8 channels; up to 96 samples per run
Design	Flow-free, no tubing maintenance required
Applications	Kinetics & affinity profiling, screening, single-cycle kinetics, small molecule analysis, fragment-based screening, epitope mapping & pairing, immunogenicity, quantitative analysis, thermodynamics, ELISA and microplate reader functionality
Refractive Index Range	1.33–1.43
Sample Volume	2–200 μL, non-destructive
Temperature Range	Ambient
Shaking Speed	200–1000 rpm
Data Display	Real-time sensorgrams, curve fitting, calibration curves, concentration tables, kinetic data tables, epitope analysis plots, bar charts
Data Export Formats	Excel, TXT
Sample Types	Small molecules, peptides, proteins, antibodies, nucleic acids, polysaccharides, lipids, viruses, cells, and crude biological samples (buffers with DMSO, plasma, serum, supernatants, lysates, etc.)
Additional Functions	Includes conventional ELISA and microplate reader functionalities

The WeSPR 100X is a versatile multifunctional detection platform that integrates SPR-based interaction analysis with ELISA-style workflows in a single, compact system. By offering high throughput, sample compatibility, and zero-maintenance flow-free design, it accelerates discovery across drug development, antibody characterization, vaccine research, and molecular mechanism studies.

Contact us today to learn how WeSPR 100X can streamline your biomolecular interaction studies while saving time and resources.

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