VSV vectors Construction/VSV Packaging for gene delivery (CAT#: STEM-MB-0012-WXH)

Introduction

Vesicular stomatitis virus (VSV) is an enveloped, negative-sense RNA virus that infects a wide variety of mammalian and insect cells. Infections in humans are asymptomatic or result in a mild febrile illness.<br />Recombinant vesicular stomatitis virus (VSV) vectors are widely used for a variety of applications including studying mechanisms of viral entry into host cells, identification of cellular receptors utilized by viruses for cell entry, screening of viral entry inhibitors and vaccine development research. VSV vectors can be efficiently pseudotyped with envelope glycoproteins derived from heterologous viruses, such as envelope proteins of viruses requiring high-level containment, thereby making them highly suitable for studying the entry mechanisms of such high-risk viruses.