TSKgel FcR-ⅢA-NPR Affinity Column, 5 µm (CAT#: STEM-BC-3228-ZJF)

Highlights

Recognizes Fc glycan structure

ADCC-related separation

Recombinant FcγRⅢA ligand

Cat Number: STEM-BC-3228-ZJF

Application: for antibody ADCC activity-related glycoform analysis

Model: TSKgel FcR-ⅢA-NPR




Description

This affinity chromatography column is designed for antibodies and Fc-fusion proteins. It uses recombinant human FcγRⅢA as the immobilized ligand. The ligand is bonded to a nonporous hydrophilic polymer matrix. It recognizes differences in N-linked glycan structures on antibody Fc regions. These structural differences influence antibody-dependent cellular cytotoxicity activity. The column separates antibodies according to Fc-receptor interaction and related biological activity. It is suitable for cell-line screening, culture optimization, upstream process monitoring, and lot-quality assessment. PEEK hardware helps reduce nonspecific adsorption during analytical operation.

Specification

Model: TSKgel FcR-ⅢA-NPR
Chromatography mode: Fc-receptor affinity
Matrix: Hydrophilic nonporous polymer
Ligand: Recombinant human FcγRⅢA
Particle size: 5 µm
Column dimensions: 4.6 mm I.D. × 7.5 cm
Column material: PEEK
Catalog number: 0023513
Applications: Antibodies, Fc-fusion proteins, glycoform analysis, and ADCC-related quality monitoring

Features

Recognizes Fc glycan structure
ADCC-related separation
Recombinant FcγRⅢA ligand
Nonporous 5 µm particles
PEEK low-binding hardware
Antibody and Fc-fusion compatibility
Cell-line screening utility
Batch-quality monitoring

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