Study of Maternal origin of inflammatory leukocytes in preterm fetal membranes by Fluorescence in situ hybridisation (FISH) (CAT#: STEM-MB-1227-WXH)

Introduction

Chorioamnionitis is a histological diagnosis based upon the infiltration of inflammatory leukocytes into the fetal membranes. It is associated with a maternal inflammatory reaction, often with fever and increased C-reactive protein (CRP) levels.
In chorioamnionitis, leukocyte infiltration is often considered to be maternal, although no studies have demonstrated this definitively. However, a fetal origin for leukocytes in amniotic fluid has been identified and such cells could possibly access the amnion or chorion of the fetal membranes.