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Stress Animal Model (CAT#: STEM-AE-0032-WXH)

Introduction

Stress refers to the non-specific systemic reaction that occurs when the body is stimulated by strong internal and external environmental factors. There is a strong link between stress and many diseases. Social stress can cause many mental and behavioral disorders, including anxiety, depression, substance abuse, and decreased sexual function. As the relationship between stress and disease has been paid more and more attention, the establishment of stress animal models has become an experimental method widely involved in the medical field.




Applications

• Mechanisms involved in studying depression
• Antidepressant Drug Research

Procedure

• Model of behavioral despair: forced swimming test, mouse tail suspension test.
• Model of learned helplessness.
• Social Stress Models: Orphanage Model, Social Failure Model.
• Chronic Mild Unpredictable Stress Stimulation (CUMS) Model (Model of chronic unpredictable mild stress): A variety of different stress factors are randomly selected every day for several consecutive days.

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