Seplife LXMS 50HQ Strong Anion-Exchange Medium, ≥70 mg BSA/mL (CAT#: STEM-BC-3110-ZJF)

This strong anion-exchange medium is designed for purification of antibodies, recombinant proteins, vaccines, blood products, viruses, DNA, and peptides. It uses a porous polystyrene-divinylbenzene polymer matrix. Quaternary amine ligands provide strong anion-exchange functionality. The rigid particles support high-pressure and high-flow operation with low backpressure. High salt tolerance increases flexibility when processing feeds with elevated conductivity. This can reduce dilution, dialysis, and ultrafiltration buffer-exchange steps. The medium provides high chromatographic resolution and stable protein-binding capacity. Its mechanical and chemical stability supports predictable scale-up. The product is suitable for capture, intermediate purification, and polishing workflows.

Model: Seplife® LXMS 50HQ
Appearance: White opaque spherical particles, odorless and tasteless
Type: Strong anion-exchange medium
Matrix: Polystyrene-divinylbenzene
Ligand: Quaternary amine
Median particle size d50v: 50 µm
Pressure-flow range: 200-800 cm/h
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common ion-exchange buffers
Ion-exchange capacity: 0.13-0.17 mmol/mL
Dynamic binding capacity: ≥70 mg BSA/mL
Maximum pressure: 30 bar
Test conditions: 10 cm bed height, 25°C, and 0.1 mol/L sodium chloride

Strong quaternary-amine exchange
High salt tolerance
Rigid 30-bar polymer matrix
High-flow operation
Low backpressure
Broad CIP pH range
Stable BSA binding capacity
Suitable for scalable purification

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