Seplife LXMS 30S Strong Cation-Exchange Medium, ≥90 mg Lysozyme/mL (CAT#: STEM-BC-3112-ZJF)

Highlights

High lysozyme capacity
Strong cation-exchange functionality
High-resolution 30 µm particles

Cat Number: STEM-BC-3112-ZJF

Application: for high-resolution cation-exchange biomolecule purification

Model: Seplife® LXMS 30S




Description

This strong cation-exchange medium is designed for purification of antibodies, proteins, peptides, and nucleic acids. It uses highly crosslinked porous polystyrene-divinylbenzene monodisperse microspheres. A hydrophilic surface layer reduces nonspecific adsorption. Sulfonic-acid ligands provide strong cation-exchange binding. The 30 µm particle size improves resolution in demanding separations. The rigid matrix supports high flow and operation up to the stated pressure. High dynamic lysozyme capacity supports productive preparative purification. Broad pH stability allows repeated cleaning-in-place. The medium can be used in capture, intermediate purification, and polishing processes.

Specification

Model: Seplife® LXMS 30S
Appearance: White opaque spherical particles, odorless and tasteless
Type: Strong cation-exchange medium
Matrix: Polystyrene-divinylbenzene
Ligand: Sulfonic-acid group
Median particle size d50v: 30 µm
Pressure-flow range: 100-900 cm/h
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common ion-exchange buffers
Ion-exchange capacity: 0.07-0.10 mmol/mL
Dynamic binding capacity: ≥90 mg lysozyme/mL
Maximum pressure: 30 bar
Test conditions: 10 cm bed height, 25°C, and 0.1 mol/L sodium chloride

Features

High lysozyme capacity
Strong cation-exchange functionality
High-resolution 30 µm particles
Rigid 30-bar matrix
High-flow operation
Hydrophilic low-binding surface
Broad CIP pH range
Suitable for scalable purification

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