Seplife LXMS 30Q Strong Anion-Exchange Medium, 30 µm (CAT#: STEM-BC-3111-ZJF)

Highlights

High-resolution 30 µm particles
Strong anion-exchange chemistry
High-flow rigid matrix

Cat Number: STEM-BC-3111-ZJF

Application: for high-resolution anion-exchange biomolecule purification

Model: Seplife® LXMS 30Q




Description

This strong anion-exchange medium is designed for capture, intermediate purification, and polishing of antibodies, proteins, peptides, and nucleic acids. It uses highly crosslinked porous polystyrene-divinylbenzene monodisperse microspheres. A chemically stable hydrophilic layer is bonded to the particle surface. Quaternary amine groups provide strong anion-exchange binding. The 30 µm particle size supports high chromatographic resolution. The rigid matrix permits high flow and elevated-pressure operation. Low nonspecific adsorption improves sample recovery. Broad pH stability supports repeated cleaning-in-place. The medium is suitable for high-efficiency downstream purification processes.

Specification

Model: Seplife® LXMS 30Q
Appearance: White opaque spherical particles, odorless and tasteless
Type: Strong anion-exchange medium
Matrix: Polystyrene-divinylbenzene
Ligand: Quaternary amine
Median particle size d50v: 30 µm
Pressure-flow range: 100-900 cm/h
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common ion-exchange buffers
Ion-exchange capacity: 0.07-0.10 mmol/mL
Dynamic binding capacity: ≥55 mg BSA/mL
Maximum pressure: 30 bar
Test conditions: 10 cm bed height, 25°C, and 0.1 mol/L sodium chloride

Features

High-resolution 30 µm particles
Strong anion-exchange chemistry
High-flow rigid matrix
Broad CIP pH tolerance
Low nonspecific adsorption
Good biocompatibility
Stable physical properties
Suitable for capture through polishing

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