Seplife LXMS 15S Sulfonic-Acid Ion-Exchange Medium, 15 µm (CAT#: STEM-BC-3113-ZJF)

This ion-exchange medium is designed for high-resolution purification of antibodies, proteins, peptides, and nucleic acids. It uses highly crosslinked porous polystyrene-divinylbenzene monodisperse microspheres. A chemically stable hydrophilic layer is bonded to the particle surface. Sulfonic-acid ligands provide cation-exchange functionality despite the source classification inconsistency. The 15 µm particle size supports very high chromatographic resolution. The rigid polymeric matrix tolerates elevated pressure and high linear flow. A dynamic lysozyme capacity of at least 90 mg/mL supports preparative use. Low nonspecific adsorption contributes to product recovery. Broad pH stability supports repeated cleaning-in-place cycles.

Model: Seplife® LXMS 15S
Appearance: White opaque spherical particles, odorless and tasteless
Listed type: Strong anion-exchange medium
Functional chemistry: Sulfonic-acid ligand indicating strong cation exchange
Matrix: Polystyrene-divinylbenzene
Ligand: Sulfonic-acid group
Median particle size d50v: 15 µm
Pressure-flow range: 100-900 cm/h
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common ion-exchange buffers
Ion-exchange capacity: 0.07-0.10 mmol/mL
Dynamic binding capacity: ≥90 mg lysozyme/mL
Maximum pressure: 30 bar
Test conditions: 10 cm bed height, 25°C, and 0.1 mol/L sodium chloride

Ultra-fine 15 µm particles
Sulfonic-acid ion-exchange ligand
High lysozyme capacity
High-flow rigid matrix
Broad CIP pH tolerance
Low nonspecific adsorption
High separation resolution
Suitable for fine purification

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