Seplife LXMS 15Q Strong Anion-Exchange Medium, 15 µm (CAT#: STEM-BC-3114-ZJF)

This strong anion-exchange medium is designed for high-resolution purification of antibodies, proteins, peptides, and nucleic acids. It uses highly crosslinked porous polystyrene-divinylbenzene monodisperse microspheres. A hydrophilic surface layer improves biocompatibility and reduces nonspecific adsorption. Quaternary amine groups provide strong anion-exchange functionality. The 15 µm particles support fine separation and high chromatographic efficiency. The rigid matrix allows operation at elevated pressure and high flow. Dynamic BSA binding capacity supports preparative purification. Broad pH stability supports repeated cleaning-in-place. The medium is suitable for capture, intermediate purification, and polishing.

Model: Seplife® LXMS 15Q
Appearance: White opaque spherical particles, odorless and tasteless
Type: Strong anion-exchange medium
Matrix: Polystyrene-divinylbenzene
Ligand: Quaternary amine
Median particle size d50v: 15 µm
Pressure-flow range: 100-900 cm/h
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common ion-exchange buffers
Ion-exchange capacity: 0.07-0.10 mmol/mL
Dynamic binding capacity: ≥55 mg BSA/mL
Maximum pressure: 30 bar
Test conditions: 10 cm bed height, 25°C, and 0.1 mol/L sodium chloride

Ultra-high-resolution 15 µm particles
Strong quaternary-amine exchange
Rigid 30-bar matrix
High-flow performance
Hydrophilic low-binding layer
Broad CIP pH range
Good biomolecule recovery
Suitable for polishing applications

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