Seplife CL-6B Crosslinked Size-Exclusion Medium, 10000-4×10⁶ Da (CAT#: STEM-BC-3178-ZJF)

This crosslinked agarose medium is designed for size-exclusion purification of proteins, nucleic acids, and peptides. It uses six-percent crosslinked agarose gel particles. Molecules are separated according to their access to the internal pore structure. The medium provides a broad globular-protein exclusion range. Low nonspecific adsorption supports product recovery during purification. The crosslinked matrix provides resistance to denaturants and multiple organic solvents. Broad pH stability supports cleaning-in-place over an extended range. The medium can be reused for repeated fractionation processes. It is suitable for samples with substantial molecular-size differences and moderate resolution requirements.

Model: Seplife CL-6B
Appearance: White spherical gel, odorless and tasteless
Matrix: 6% crosslinked agarose gel
Globular-protein exclusion range: 10000-4×10⁶ Da
Particle size: 45-165 µm
Pressure-flow range: 110-210 cm/h at 0.15 MPa
Long-term pH stability: 3-13
Short-term CIP pH stability: 2-14
Chemical compatibility: 8 mol/L urea, 6 mol/L guanidine hydrochloride, ethanol, DMF, THF, DMS, chloroform, acetone, pyridine, dimethylformamide, dichloroethane, and acetonitrile
Heat resistance: 120°C in pH 7 water for 20 min

Broad solvent compatibility
Crosslinked agarose matrix
Wide CIP pH range
Broad exclusion range
Low nonspecific adsorption
Reusable gel particles
Moderate process flow
Suitable for biomolecule fractionation

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