Cup ultrasonic mill, also called non-contact type. Non-contact cup-shaped container (suitable for handling biohazardous and hazardous samples) with a sound-absorbing hold-down device. Compared with the traditional probe ultrasonic cell crusher, the probe is in direct contact with the sample, and the same probe needs to be reused, which is easy to cause cross-contamination of the sample. Due to the different depth of insertion of the probe into the sample each time, the energy distribution of each ultrasonic wave is also different, which affects the repeatability and accuracy of the experimental results. Multiple samples can be detected at one time, with high experimental efficiency; no need to frequently operate the probe, each sample is in a separate fully enclosed test tube to avoid cross-contamination; optional SDC-6 cryogenic bath, convenient for samples in 4 OC water bath ultrasonic , the energy distribution is uniform, the ultrasonic effect is complete; the ultrasonic parameter setting is flexible, the experimental steps are standardized, the experiment repeatability is good, and the result is highly reliable. It has gradually become an indispensable standardized tool for ChIP (chromatin immunoprecipitation) and DNA shearing research platforms. High experimental efficiency, reliable results, and good repeatability. It can process a minimum of 5ul samples, and is suitable for precious samples.