Recombinant Human FGF-8b Protein, Seafrom (CAT#: STEM-CT-0050-ZJF)

The Recombinant Human FGF-8b Protein manufactured by Seafrom is suitable for cell growth, development, and tissue repair.
FGF-8 (FGF-8b) is a heparin-binding growth factor belonging to the FGF family. Proteins in this family play a central role in prenatal development, postnatal growth, and tissue regeneration by promoting cell proliferation and differentiation. FGF8 has four known alternative splicing forms: FGF8A, FGF-8B, FGF-8E, and FGF-8F. Human and mouse FGF-8A and B are identical, while human and mouse FGF-8E and FGF-8F share 98% similarity. FGF-8 primarily targets breast cancer cells and other cells expressing FGF receptors.
The lyophilized formulation can be stored at 4°C for 24 months. Once reconstituted, the liquid can be stored at -20°C for 6-12 months, avoiding repeated freeze-thaw cycles.

Expression Host: Human HEK293 Cells
Synonyms: Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF-8
Protein Sequence: DNA sequence encodes human FGF-8b (NP_149355.1) with an Fc tag at the C-terminus, contains 431 amino acids, predicted molecular weight of 49.3 kD
Purity: ≥95%, analyzed by SDS-PAGE and HPLC
Endotoxin Level: ≤0.01 EU/μg (gel clot method)
Biological Activity: ED50 determined by dose-dependent stimulation of thymidine in BaF3 cells expressing FGF receptors, should be ≤1 ng/mL, with a specific activity of ≥1x10^6 IU/mg
Purification Method: Chromatographic purification

Stable Cell Library
Large-Scale Expression
High Activity
Batch Stability
Gmp-Quality Control
Ensured Product Quality

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