Recombinant Human BCMA Protein, Seafrom (CAT#: STEM-CT-0102-ZJF)

The Recombinant Human BCMA Protein manufactured by Seafrom is suitable for B-cell activation and antibody production.
Tumor necrosis factor receptor superfamily member 17 (TNFRSF17), also known as B-cell maturation antigen (BCMA) and CD antigen CD269, is a member of the TNF receptor superfamily. TNFRSF17 contains a TNFR-Cys repeat sequence. TNFRSF17 is expressed in mature B cells but not in T cells or monocytes. It serves as the receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. TNFRSF17 promotes B cell survival and plays a role in regulating humoral immunity. TNFRSF17 can activate NF-κB and JNK.
The lyophilized product can be stored at 4°C for 24 months, and the reconstituted liquid can be stored at -20°C for 6-12 months, avoiding repeated freeze-thaw cycles.

Expression Host: Human HEK293 cells
Source: Human
Synonyms: TNFRSF17, CD269, BCM, BCMA
Protein Sequence: The DNA sequence encodes BCMA (UniProtKB - Q02223), expressed with an FC tag at the C-terminus.
Molecular Weight: Recombinant BCMA protein consists of 268 amino acids, with a predicted theoretical molecular weight of 32.3 kD.
Purity: ≥95%, confirmed by SDS-PAGE gel and HPLC analysis.
Endotoxin: <0.1 EU/μg
Biological Activity (ELISA): The linear range for binding of BCMA protein is at 1 μg/mL (100 μL/well), and the binding range with anti-human BCMA monoclonal antibody is 0.1-1.0 ng/mL.
Purification Method: Chromatographic purification
Composition: Sterile PBS (pH 7.4) freeze-dried powder containing 6% mannitol.

Optimal Stability
Gmp-Grade Quality
Low Batch-to-Batch Variability
Exceptional Specificity
Robust Bioactivity
Efficient and Reliable Performance

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