The Recombinant FITC-Labeled Human EGFR/HER1 Protein, His-Avi Tag manufactured by Yisheng is suitable for detecting EGFR/HER1-positive cells in research. The EGFR (Epidermal Growth Factor Receptor) subfamily of receptor tyrosine kinases comprises four members: EGFR (HER-1), ErbB2, ErbB3, and ErbB4. EGFR binds a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, HB-EGF, and epigen. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, heterodimerization, tyrosine phosphorylation, and cell signaling.
Specification
Synonyms: ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2 Uniprot No.: P00533-1 Source: Recombinant FITC-Labeled Human EGFR/HER1 Protein is expressed from HEK293 Cells with His tag and Avi tag at the C-terminal. It contains Leu25-Ser645. Molecular Weight: The protein has a predicted MW of 71.5 kDa. Due to glycosylation, the protein migrates to 90-115 kDa based on Tris-Bis PAGE result. Purity: > 95% as determined by SDS-PAGE. Endotoxin: < 1.0 EU per 1μg of the protein by the LAL method. Formulation: Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Features
Shipped with ice pack. Stored at -25~-15℃ for 1 year from date of receipt. 2-7 days, 2 ~8 ℃ under sterile conditions after reconstitution. 3 months, -25~-15℃ under sterile conditions after reconstitution. Recommend to aliquot the protein into smaller quantities when first used and avoid repeated freeze-thaw cycles. For safety and health, please wear lab coats and disposable gloves for operation.
Related Products
Recombinant PE-Labeled Human EGFRVIII Protein, His-Avi Tag, Yisheng Recombinant FITC-Labeled Human BCMA Protein, His-Avi Tag, Yisheng Recombinant FITC-Labeled Human MSLN/Mesothelin , His-Avi Tag, Yisheng Recombinant FITC-Labeled Human Siglec-2/CD22 Protein, hFc TagRecombinant FITC-Labeled Human Siglec-2/CD22 Protein, hFc Tag, Yisheng