Q Seplife HP Strong Anion-Exchange Medium, 24-44 µm (CAT#: STEM-BC-3162-ZJF)

This strong anion-exchange medium is designed for downstream purification of proteins, nucleic acids, and peptides. It uses a highly crosslinked agarose matrix functionalized with quaternary ammonium groups. The permanently charged ligand provides strong anion-exchange binding over a broad operating range. The 24-44 µm particles improve mass transfer and chromatographic resolution. A BSA adsorption capacity above 70 mg/mL supports preparative capture and polishing. The medium provides flow above 150 cm/h under the stated test conditions. Low nonspecific adsorption contributes to product recovery and separation consistency. Broad chemical and pH stability support repeated cleaning, regeneration, and steam treatment.

Model: Q Seplife HP
Appearance: White spherical gel, odorless and tasteless
Type: Strong anion-exchange medium
Matrix: Seplife 6FF
Ligand: Trimethylaminoalkyl quaternary ammonium group
Particle size: 24-44 µm
BSA adsorption capacity:>70 mg/mL
Ion-exchange capacity: 0.14-0.20 mmol/mL
Maximum flow rate:>150 cm/h
Pressure resistance: 0.3 MPa
Operating temperature: 4-40°C
Long-term pH stability: 2-12
Short-term CIP pH stability: 1-14
Chemical compatibility: Common aqueous buffers, 1 mol/L sodium hydroxide, 8 mol/L urea, 8 mol/L guanidine hydrochloride, and 70% ethanol
Heat resistance: 121°C in water for 30 min

High-resolution 24-44 µm particles
Strong quaternary-amine exchange
>70 mg/mL BSA capacity
Broad CIP pH tolerance
Low nonspecific adsorption
Stable agarose matrix
Steam-treatment compatibility
Suitable for capture and polishing

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