Oligo dT(25) Magnetic Microspheres, 2-3 µg mRNA/mg (CAT#: STEM-BC-3094-ZJF)

These Oligo dT magnetic microspheres are designed for selective extraction of messenger RNA. They use monodisperse polystyrene-based particles containing embedded magnetite. The encapsulation process limits magnetic-material leakage that could interfere with downstream enzyme activity. A specialized surface provides low nonspecific adsorption during nucleic-acid purification. Oligo dT(25) chains are covalently attached to the particle surface. The immobilized oligonucleotides bind strongly to Poly(A) tails on mRNA molecules. Covalent ligand attachment provides stability and supports repeated use under appropriate conditions. The particles are available in two sizes and provide a defined mRNA-binding capacity.

Model: Oligo dT Magnetic Microspheres
Matrix: Polymer and Fe3O4
Particle sizes: 1 and 3 µm
Surface functional group: Covalently bound Oligo dT(25)
Binding capacity: 2-3 µg mRNA per mg of microspheres or 10-15 µg mRNA per mL of suspension
Microsphere concentration: 5 mg/mL
Magnetic content: 28%
Target molecule: Poly(A)-containing mRNA
Primary application: mRNA extraction

High Poly(A) binding affinity
Covalently immobilized Oligo dT(25)
Low nonspecific adsorption
Minimal magnetic-material leakage
Compatible with downstream enzymes
Stable magnetic response
Defined mRNA capacity
Potential for repeated use

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