OCT3/4 Signaling Pathway Luminex Assay (CAT#: STEM-MB-0328-WXH)

Oct3/4 is regarded as one of the key regulators of pluripotency. Oct-4 is a homeodomain transcription factor of the POU family. This protein is critically involved in the self-renewal of undifferentiated embryonic stem cells. it is frequently used as a marker for undifferentiated cells. Oct-4 expression must be closely regulated; too much or too little will cause differentiation of the cells.
Oct-3/4 is a POU transcription factor that is expressed in embryonic stem (ES) cells and germ cells, and its expression is required to sustain cell self-renewal and pluripotency. Oct-3/4 is the most recognized marker for totipotent ES cells.

To study the regulation mechanism of OCT3/4 signal pathway in disease
To study the effect of each virus on OCT3/4 signaling pathway
To study the effects of drugs or therapies on OCT3/4 signaling pathways

• Luminex Multiplex Assay
• Enzyme-linked immunosorbent assay (ELISA)
• Flow cytometry (FACS analysis) technology

Detectable targets: ATG13, ATG2, ATG12, ATG5, ATG7, ATG10, ATG3, ATG4, JNK, MYD88, Rac1, TLR4, LC3I, WIPi2, ATG16, PROLC3, ULK, FIP200, VPS15, VPS34, UYRAG, NFκB, RIG-1, TRAF3, GAS, IRF9, AMBRA1, p38, RIP1, TRAF5, Histone-H3, IRF5, MEK3, p38MAPK, SH2, TRAF6, IKK-α, IRS1, MEK6, p50, SLP76, TRAM, TLR3, IRS2, MSK1, p65, Tak1, TRIF, IPS-1, ISGF3, MSK2, PI3K, TBK1, Vav, IRAK1, ISRE, mTOR, PKR