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Myocardial Ischemia Animal Model (CAT#: STEM-AE-0044-WXH)

Introduction

Cardiovascular disease is one of the diseases with a high mortality rate in humans, and ischemic cardiomyopathy plays a leading role in it.<br />Clinically, acute myocardial ischemia mainly manifests as symptoms such as acute angina pectoris and acute myocardial infarction, and severe cases may endanger the lives of patients. The acute myocardial ischemia model is a short-term experimental model established based on the clinical characteristics of myocardial ischemia. The available modeling methods include open-chest surgery modeling, closed-chest surgery modeling and drug modeling.




Applications

This model is used for the research of prevention and treatment drug screening, as well as the research of drug effect experiment and treatment of myocardial ischemia.

Procedure

• Drug method: pituitary hormone (Pit), isoproterenol (Iso).
• Coronary artery ligation method.
• Intracoronary embolization method.
• Mechanical compression of coronary arteries.
• Electrical stimulation.

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