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Microinjection is a method for mechanically injecting cells, genetic material, peptides, drugs, or other exogenous agents directly into cells or tissues using a very small pipette. Conversely, material may also be removed from the sample (e.g., enucleation of cells). Microinjection has numerous research and clinical applications, including transfection of cells via DNA injection, fertilization by intracytoplasmic sperm injection (ICSI), introduction of genetically engineered embryonic stem cells into a blastocyst, and more.
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