Homogeneity studies of Thyroglobulin by Dynamic light scattering (DLS) (CAT#: STEM-MB-0533-WXH)

Introduction

Thyroglobulin (Tg) is a 660 kDa, dimeric glycoprotein produced by the follicular cells of the thyroid and used entirely within the thyroid gland. Thyroglobulin (Tg) acts as a substrate for the synthesis of the thyroid hormones thyroxine (T4) and triiodothyronine (T3), as well as the storage of the inactive forms of thyroid hormone and iodine within the follicular lumen of a thyroid follicle.
Homogeneity is one of the most basic and important protein properties in general life science and biopharmaceutical applications. In an ideal study, the protein of interest would exist throughout the sample in a consistent form and size to ensure optimal purity for accurate characterization.