Homogeneity studies of nidogen-1 (ND-1) by Dynamic light scattering (DLS) (CAT#: STEM-MB-0531-WXH)

Introduction

Nidogen-1 (ND-1) is a key basement membrane protein that primarily interacts with other ECM proteins such as laminin, perlecan, fibulin, and fibronectin. Nidogen-1 is a member of the nidogen family of basement membrane glycoproteins. The protein interacts with several other components of basement membranes. Structurally it (along with perlecan) connects the networks formed by collagens and laminins to each other. It may also play a role in cell interactions with the extracellular matrix.<br />Homogeneity is one of the most basic and important protein properties in general life science and biopharmaceutical applications. In an ideal study, the protein of interest would exist throughout the sample in a consistent form and size to ensure optimal purity for accurate characterization.