Heparin Seplife LXPM5504 Affinity Medium, ≥5 mg Antithrombin III/mL (CAT#: STEM-BC-3129-ZJF)

This heparin affinity medium is designed for purification of biological molecules that interact with sulfated polysaccharides. It uses a polymethyl methacrylate matrix with a hydrophilically modified surface. Sodium heparin is coupled through a long spacer arm to reduce steric hindrance. The ligand can bind antithrombin III, coagulation factors, lipoproteins, interferons, nucleic-acid-binding proteins, restriction enzymes, thrombin, and related molecules. The long spacer improves ligand accessibility and binding capacity. The hydrophilic surface reduces nonspecific adsorption during chromatography. The rigid 80 µm particles support flow from 100 to 800 cm/h and pressure up to 0.8 MPa. The medium is stored in buffered aqueous ethanol at refrigerated temperature.

Model: Heparin Seplife® LXPM5504
Matrix: Polymethyl methacrylate
Ligand: Sodium heparin
Particle size: 80 µm
Pore size: 1000 Å
Ligand density: ≥5 in the source-stated unit
Binding capacity: ≥5 mg antithrombin III/mL
Maximum pressure: 0.8 MPa
Recommended flow: 100-800 cm/h
pH stability: 4-10
Storage: 20% ethanol containing 0.05 mol/L sodium acetate at 4-8°C

Long-chain heparin spacer
Specific heparin-binding affinity
≥5 mg/mL antithrombin capacity
Low nonspecific adsorption
Rigid polymeric matrix
Up to 800 cm/h flow
Suitable for diverse biomolecules
Refrigerated buffered storage

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