GE Biacore S200 High Throughput SPR Analyzer, Cytiva (CAT#: STEM-CTEPO-0062-ZJF)

The GE Biacore S200 High Throughput SPR Analyzer is manufactured by Cytiva.
The Biacore S200 is the most sensitive SPR-based sensor for cutting-edge applications and offers exceptional data quality using small sample volumes. Predefined run and evaluation templates guide the user and shorten time to results. This unit comes fully certified with a 90- day warranty. A computer preloaded with software is also included.

Condition: Certified pre-owned
Detection technology: Surface plasmon resonance (SPR) biosensor
Information provided: Kinetic and affinity data (KD, ka , and kd ), specificity, selectivity, thermodynamics and screening data
Data presentation: Result tables, result plots, and real-time monitoring of sensorgrams
Analysis time per cycle: Typically 2 to 15 min
Automation: 48 h unattended operation
Sample type: LMW drug candidates to high molecular weight proteins (also DNA, RNA, polysaccharides, lipids, cells, and viruses) in various sample environments (e.g., in DMSO-containing buffers, plasma, and serum)
Required sample volume: Injection volume plus 20 to 50 μL (application dependent)
Injection volume: 2 to 350 μL
Flow rate range: From 1 to 100 μL/min
Flow cell volume: 0.06 μL
Data collection rate: 1, 10, or 40 Hz
Flow cell height: 40 μm
Sample/reagent capacity: 1 × 96- or 384-well microplate and up to 33 reagent vials or 78 vials for samples and reagents
Typical run time:
Clean screen (384-well plate): 6 h
Binding level screen (384-well plate): 15 h
Affinity screen (384-well plate): 25 h
Kinetic analysis: 30 samples in 16 h
Analysis temperature range: 4°C to 45°C (maximum 20°C below ambient temperature)
Sample storage: 4°C to 45°C (maximum 15°C below ambient temperature)
Sample refractive index range: 1.33 to 1.40
Buffer selector: Automatic switching between four buffers
In-line reference subtraction: Automatic
Warranty: 90-day warranty

Exceptional sensitivity that facilitates work with difficult targets where response levels are low and in small sample volumes
384 single-concentration fragment binding data in less than 16 h
Competition assays for validation of binders and for binding-site mapping
Affinity and kinetics determinations with exceptional quality for confident lead optimization

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