Diabetic Animal Model (CAT#: STEM-AE-0079-WXH)

Introduction

Diabetes mellitus (DM) has become the third major chronic disease that threatens human health after cancer and cardiovascular disease. Diabetes is a chronic disease that occurs when glucose levels rise due to the body's inability to secrete or produce enough insulin or to use insulin effectively.

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Principle Applications Procedure Materials Notes Related Products

Applications

• Study the pathogenesis and treatment of diabetes.
• Drug development, drug screening and efficacy research.

Procedure

• Surgical Induction: Removal of the Pancreas.
• Chemo-induced: Injection of streptozotocin STZ.
• Transgenic model.
• Diet Induction: High Fat Diet.
• Spontaneous diabetes animal models:
Type I diabetes--NOD (non obesity diabetes) mice.
Type II diabetes--OLETF rats, db/db mice, KK-Ay mice.

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