Determination of Melting Point of Novel Schiff Base Derivatives of Benzothiazepine by Open Capillary Method (CAT#: STEM-PPA-0082-YJL)

Introduction

As estimated by WHO, depression shall become the second largest illness in terms of morbidity by another decade in the world; already one out of every five women, and every twelve men have depression. Not only adults, but two percent of school children, and five percent of teenagers also suffer from depression, and these mostly go unidentified. Depression has been the commonest reason why people come to a psychiatrist, although the common man's perception is that all psychological problems are depression. Current treatments for depression either fail to produce recovery or induce unwanted side effects. So there is still a large unmet clinical need. The main aims in the development of new antidepressants are greater efficacy, absence of side effects, lack of toxicity in over dose and earlier onset of action.