Convulsion Animal Model (CAT#: STEM-AE-0031-WXH)

• Mechanisms involved in studying convulsions.
• Convulsion-related drug development, drug screening and efficacy research.

1. Pentylenetetrazol-induced convulsion model: Pentetrazol mainly acts on the brainstem and brain, enhancing the facilitation process of excitatory synapses and causing convulsions.
2. Chronic ignition of pentetrazol in rat convulsion model.
3. Strychnine-induced convulsion model in mice: strychnine is an antagonist of glycine receptors of spinal cord inhibitory neurons, which can selectively excite the spinal cord, and high-dose intraperitoneal injection can cause epilepsy-like tonic convulsions in animals.
4. Electrical stimulation induced convulsion model in mice: electrical stimulation induced convulsions in mice, and the animals developed tonic convulsions after electrical stimulation.
5. Rat febrile convulsion model in the developing stage: the febrile convulsions of the rats were induced by a hot water bath, and the animals developed tonic convulsions after electrical stimulation.
6. Auditory-induced convulsions model: Strong bell stimulation causes excessive excitement of the auditory center, which then spreads to the adjacent motor centers, causing certain sensitive animals to produce a stereotyped motor seizure.
7. Semicarbazide-induced convulsion model in mice.