Cleaning verification of pharmaceutical equipment by combustion oxidation and non-dispersive infrared absorption method (CAT#: STEM-PPA-0104-LJX)

Because there are many kinds of organic carbon in water, it is difficult to determine the organic carbon content directly. Therefore, it is necessary to oxidize organic carbon into inorganic carbon to determine. The determination principle of total organic carbon in water is: the organic material molecules in water are completely oxidized to carbon dioxide (CO2), the amount of carbon dioxide generated is detected, and then the concentration of organic carbon in water is calculated.
Combustion oxidation and non-dispersive infrared absorption method is to determine the total organic carbon content of liquid by the oxidation of organic carbon to inorganic carbon in the way of high temperature combustion. The method has the advantages of simple operation, good repeatability and high sensitivity, so it is widely used.

For the determination of total organic carbon in liquids

1. The sample is introduced into a high-temperature combustion tube for catalytic oxidation, so that both organic compounds and inorganic carbonates are converted into carbon dioxide
2. The carbon dioxide generated by the decomposition of inorganic carbonate is introduced into the non-dispersive infrared detector
3. Because a certain wavelength of infrared can be selected by carbon dioxide absorption, in a certain concentration range of carbon dioxide absorption of infrared is proportional to the concentration of carbon dioxide, so the total carbon (TC) and inorganic carbon (IC) of the water sample can be quantitatively determined
4. The difference between total carbon and inorganic carbon is the total organic carbon (TOC)

• Sample Type:
Cleanser

According to the instructions of the instrument manufacturer, regularly replace the carbon dioxide absorber, the catalyst in the high temperature combustion tube and the decomposition agent in the low temperature reaction tube.