circRNA Microarray (CAT#: STEM-MB-0144-WXH)

Introduction

Circular RNA (circRNA) is a type of non-coding RNA formed by a special splicing mechanism with a closed loop structure and abundantly present in eukaryotic transcriptomes. It is also a research hotspot in the fields of life science and medicine. Generally, most circRNAs function as miRNA sponges or transcription/translation regulator to impact the expression of miRNA target genes, which plays important roles in the regulation of cancers. With the widespread application of RNA sequencing (RNA-seq) technology and bioinformatics prediction, large numbers of circRNAs have been identified. However, low abundance expression level of circRNA significantly limits the detection efficiency of RNA-seq. Therefore, high-throughput microarray may act as a more sensitive, efficient and cost-effective technology for circRNA expression profiling.