Analysis of Renin (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0523-LGZ)

Introduction

Renin, also known as angiotensinogen enzyme, is involved in the renin-angiotensin system (RAS) of the body. The expression gene of renin is located in 1q32.1, and the main function of Renin is to cause increased blood pressure and intrarenal recovery of perfusion pressure. Renin catalyzes the first step in the angiotensinogen activation pathway, a series of reactions that eventually lead to aldosterone release and vasoconstriction. Renin cleaved angiotensinogen to produce angiotensin I through rate-limiting reaction, and then was catalyzed by angiotensin I converting enzyme to produce angiotensin II. RAS plays an important role in regulating blood pressure and maintaining electrolyte balance.