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Analysis of Regenerated silk fibroin films by Thermal Gravimetric Analysis (TGA) (CAT#: STEM-ACT-0047-WXH)

Introduction

Regenerated silk fibroin (RSF) is a nonphysiological natural biological macromolecule derived from silk that has obvious advantages over other natural macromolecules. Furthermore, RSF has good biocompatibility and is nontoxic, nonpolluting, nonirritating, and biodegradable. Studies have shown that RSF facilitates cell adhesion while reducing inflammation.




Principle

Thermogravimetric analysis or thermal gravimetric analysis (TGA) is a method of thermal analysis in which the mass of a sample is measured over time as the temperature changes. This measurement provides information about physical phenomena, such as phase transitions, absorption, adsorption and desorption; as well as chemical phenomena including chemisorptions, thermal decomposition, and solid-gas reactions (e.g., oxidation or reduction).

Applications

• Thermal characterization of polymers.
• Determination of the composition of alloys and mixtures.
• Determining the purity and thermal stability of both primary and secondary standards.

Procedure

TGA analysis is performed by gradually raising the temperature of a sample in a furnace as weight is measured on an analytical balance that remains outside the furnace. Thermogravimetric analysis instrument measures the changes in a sample's weight in a particular temperature by enclosing the sample in an oven.

Materials

Thermogravimetric analyzer