Analysis of Platelet by Flow Cytometry (CAT#: STEM-CBT-0075-WXH)

Introduction

Platelet-associated immunoglobulin assays by flow cytometry can be direct or indirect assays, similar to other platelet-associated immunoglobulin immunoassays. Flow cytometry is an excellent method for direct analysis of platelet-bound antibodies, and it has also been shown to be of benefit in detection of free plasma antibodies<br />1. Quantify immature platelets<br />The use of thiazole orange, a fluorescent dye that binds RNA, allows immature platelets (also referred to as reticulated platelets) to be quantified<br />2. Diagnosis of primary thrombocytopathies<br />3. Functional analysis of platelet activation <br />Platelet activation may be clinically important in stored blood components, after cardiopulmonary bypass and renal dialysis, and in the treatment of patients with myocardial infarction or thrombotic events