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Analysis of IGF-2R/CI-M6P-R (Human) by MSD Hypersensitive Multi-Factor Electrochemiluminescence Analyzer (CAT#: STEM-MB-0278-LGZ)

Introduction

Insulin-like growth factor 2 receptor (IGF2R), also known as cation-independent mannose-6-phosphate receptor (CI-MPR), is a protein encoded by the IGF2R gene. It is a multifunctional protein receptor. The function of IGF2R is to clear IGF2 from the cell surface to attenuate signaling and to transport lysosomal acid hydrolase precursors from the Golgi apparatus to lysosomes.

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Principle Applications Procedure Materials

Principle

MSD electrochemiluminescence technology is mainly based on ultra-sensitive multi-factor electrochemiluminescence analyzer MES0 Sector600 or Quickplex SQ120. Through dot matrix technology, the detection of 10 indicators per well can be realized in the 96-hole graphite electrode plate. It can also be customized to realize the screening detection of 100 index wells in a 24-well plate.

Applications

Oncology & Cancer, Metabolic

Procedure

1. Coat the capture antibody on the well plate.
2. Add samples/calibrators.
3. Add detection antibody.
4. Read the plate and analyze the data.

Materials

• Sample Type: Plasma, Serum
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Wide range of applications

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