Allegro™ CM150 Single-Use Tangential Flow Filtration System (CAT#: AM-BP-0002-LC)

The Allegro CM150 single-use tangential flow filtration (SUTFF) system containing pressure, flow, conductivity, temperature and ultraviolet (UV) single use sensors is easily to be used for running ultrafiltration (UF) and diafiltration (DF) processes from 2 to 20 L batches.

Membrane area: 0.1- 0.4 m2, operating in typical crossflow range of 5 to 7 L/min/m2 Pall Centramate T-series cassettes or equivalent; Pall Cadence SUTFF modules.
Tubing internal diameter: Feed/ retentate tube: 3⁄8 in. (9.6 mm)
Permeate tube: ¼ in. (6.4 mm)
Retentate vessel: 5 L or 10 L Allegro biocontainers, for larger process volumes system may be operated in fed batch mode.
Operating temperature: 4 – 40 °C
Operating pressure: 4 barg for high pressure reinforced section on feed and retentate manifolds
1 barg permeate and medium pressure manifolds; 0 barg for biocontainers
Protection for over pressure: Yes
Minimum working volume: Minimum recirculation volume approximately: 105 mL (Estimated with 0.1 m2 Pall membrane surface area installed). Volume in feed and retentate line: 98 mL
Non recoverable volume: Approximately: 10 mL (Hold-up volume will increase by ~ 10 mL / 0.1 m2 of installed Pall membrane)
Process Wetted Components: Materials of Construction
Tubing: Platinum cured silicone tube, reinforced
Recirculation pump: Head: Polypropylene; Diaphragm: ethylene propylene diene monomer (EPDM)/ Polypropylene compound, Valves: EPDM
connections: Polysulfone, silicone
Fittings, distribution plates: Polypropylene
Pressure sensor, UV sensor: Polysulfone
Temperature sensor: Polysulfone with stainless steel sensor and silicone ring
Flow sensor: PVDF with ruby bearing
Conductivity sensor: Polysulfone with gold electrode
Sanitary fittings (tri-clamp):
connection: Polypropylene
Gaskets: Silicone

Ease of use
Single-use sensors include pressure, flow, conductivity, temperature and ultraviolet (UV)
100 mL low feed / retentate volume
Good product recovery
Cassette surface areas range from 0.1-0.4 m