S6 Kinase Signaling Pathway Assay (CAT#: STEM-MB-0319-WXH)

S6 kinase is an important member of the cell signaling pathway. A 90 kD protein kinase was first identified in African clawed toad eggs, which phosphorylates the 4OS ribosomal subunit S6 protein, thereby promoting the translation of certain mRNAs and playing an important role in the regulation of cell growth and proliferation.
S6 kinase is a substrate of ex tracellular signal-regulated kinases (ERK) and belongs to the threonine/serine kinase family. It also acts as an important primary effector downstream of the Raf-M EK-ERK cascade signaling pathway, regulating not only cell cycle, gene transcription and maintenance of cell survival, but also cell division, survival and differentiation by phosphorylating intracellular proteins in a variety of cellular pathological and physiological processes.

Study the regulatory mechanism of S6 kinase signaling pathway in clinical diseases
Research on the effects of various medical viruses on the S6 kinase signaling pathway
Study the effect of carcinogenic drugs or therapies on the S6 kinase 1 signaling pathway

• Luminex Multiplex Assay
• Enzyme-linked immunosorbent assay (ELISA)
• Flow cytometry (FACS analysis) technology

Detectable targets: Fas, ISRE, mTOR, PKR, RIG-1, TRAF3, GAS, IRF9, MEKK1, p38, RIP1, TRAF5, MHC-II, IRS1, MEK6, p50, SLP76, TRAM, RTK, PI3K, TYK2, STAT1, STAT2, STAT3, TNFR, ISGF3, MSK2, PI3K, TBK1, Vav, PSGL1, IRS2, MSK1, TLR3, Tak1, TRIFN, CD3, IRF5, MEK3, p38MAPK, SH2, TRAF6, TCR, icam1, Mda-5, NFκB