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Möbius® Zeta Potential Analyzer, Wyatt Technology Corporation (CAT#: STEM-LE-2004-LC)

Highlights

Identify and prevent degradation of fragile biomolecules during PALS analysis through simultaneous DLS measurement and low applied fields
Obtain true size/zeta-potential distributions with online fractionation
Determination of size and zeta potential of fluorescentlytagged nanomedicines with the optional fluorescence-blocking filter

Cat Number: STEM-LE-2004-LC

Application: Zeta potential analysis

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Description

Mobius provides sensitive and powerful measurements in batch, stop-flow and full-flow modes. The Mobius simultaneously performs dynamic light scattering (DLS) and phase analysis light scattering (PALS) for determination of size and zeta potential with maximum versatility.

Specification

Type:MP-PALS
Detector(s):Integrated DLS
Light Source:Power settings 10% or 100% of maximum
Sample Type:Aqueous
Measurement Mode(s):Mobility, DLS
Particle Size:Mobility Size Range:
2 nm to 50 µm
DLS Size Range:
0.2 to 5000 nm (flow cell)
0.2 to 200 nm (dip cell, quartz cuvette)
0.2 to 250 nm (disposable cuvette)
Measuring Time:1 to 3600 sec
Dimensions:(WxDxH) 36 x 60 x 21 cm
Detection System:DLS Detection: Avalanche photodiode at 163.5º scattering angle
PALS Detection: Detectors at 31 angles for MP-PALS
Wavelength(s):532 nm

Features

Identify and prevent degradation of fragile biomolecules during PALS analysis through simultaneous DLS measurement and low applied fields
Obtain true size/zeta-potential distributions with online fractionation
Determination of size and zeta potential of fluorescentlytagged nanomedicines with the optional fluorescence-blocking filter
Measurement of size and colloidal stability of nanodrug carriers in a DoE formulation matrix
Testing of the electrophoretic mobility of slurries prepared in a series of solvents
Assessment of protein charge under multiple excipients
Evaluation of pH-, concentration- and temperaturedependent behavior