CRISPR/Cas9 Knockout Cell Lines (CAT#: STEM-MB-0080-WXH)

Introduction

Stable cell lines play an important role in recombinant protein production, antibody production, drug screening, gene function research and other aspects. Stable cell lines can continue to grow and continue to stably express foreign genes. According to the direction of research or application, the expression level of exogenous genes in target cells can be regulated by changing the inserted copy number and promoter activity, making it increase, decrease, or equal to the expression level of endogenous genes in target cells. The insertion method of exogenous gene can be divided into random insertion or insertion at a fixed point.<br />Technical advantages<br />1. It can realize the simultaneous knockout of multiple target gene loci and multiple genes<br />2. The latest Nickase enzyme/dual gRNA technology significantly reduces the off-target rate<br />3. No species restriction, suitable for targeted knockout of various cell lines